I began reading Jerry Avorn's 'Powerful Medicines: The benefits, risks, and costs of prescription drugs' before Vioxx and Celebrex made headlines for their possible effects on cardiac risk. Though I'm only a third of the way through the book, I want to pass along my recommendation. So far, I've gained real insights into how drugs are tested, 'approved' by the FDA, and marketed using examples such as Fen-phen, Premarin, Rezulin and others. I'm embarrassed to say that I didn't know a tenth of what actually goes/went on (and I'm a medical doctor!). You'll be amazed, too.