One Shot Eases Pain After Surgery

Posted by Clark Venable on 10/30/2004

It is well known that the injection of a small dose of morphine into the epidural space or cerebral spinal fluid can provide significant post-operative pain relief for as long as 24 hours. The FDA has approved a liposome formulation of morphine that can double that duration. DepoDur, a morphine sulfate extended-release liposome injection, was approved in May, 2004.

""The recommended dose is 10 mg for caesarean section, 10-15 mg for lower abdominal surgery and 15 mg for major orthopaedic surgery of the lower extremities. Some patients may benefit from a dose of 20 mg.
The most common adverse events reported during clinical trials were decreased oxygen saturation, hypotension, urinary retention, vomiting, constipation, nausea, pruritus, pyrexia, anemia, headache and dizziness.""

More information at SkyePharma.

[Via Yahoo! News: Health]

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